PDB Lab

Protein Data Base (PDB) Lab,
1. Learn how to visualize protein structures using Jmol/JSmol software. Get started here: Jmol training

2. Next use the PDB to find the structure of Influenza Hemagglutinin, 5hmg.pdb, and then build a 3D model of the backbone of amino acids for 1-160 of hemagluttin B. Then, add significant features (aa side chains) to your 3D structure. http://cbm.msoe.edu/scienceOlympiad/designEnvironment/prebuild.html

3. Explain the significance of the added structural features in a short description of your model. Be sure to explain how the function of the protein is related to the structure. Go to this website for more information about this protein.
http://cbm.msoe.edu/scienceOlympiad/participant2.php
http://cbm.msoe.edu/scienceOlympiad/designEnvironment/prebuild.html

4. Give a brief summary of the chemistry that drives protein folding.

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